Cell BiologybioRxivPreprint
Intrinsic mechanotransduction during apical constriction licenses lineage competence in pluripotent stem cells
Mehdi S. Hamouda, Céline Labouesse, George W. Wylde…·Kevin J. Chalut
This study shows that mechanical forces during epithelialization in pluripotent stem cells drive nuclear changes that prime neuroectodermal lineage commitment.