Yekaterina A. Miroshnikova

The paper investigates how different routes to whole-genome duplication (WGD) affect nuclear stability, finding that mitotic slippage uniquely causes nuclear instability.

This study shows that restoring mechanophenotype or targeting YAP/TAZ can reverse malignant properties of vocal fold cancer by reducing nuclear YAP and β-catenin levels.

This study shows that mechanical forces during epithelialization in pluripotent stem cells drive nuclear changes that prime neuroectodermal lineage commitment.

The paper shows that mechano-osmotic changes in pluripotent stem cells influence chromatin state and fate transitions by integrating mechanical and biochemical signals.

This study uses deep learning and spatial data to show how tumor architecture and cell states co-evolve, influencing colorectal cancer outcomes.

This study identifies a BMAL1-YAP transcriptional complex that hijacks enhancers in aged epidermis to promote inflammation by rewiring chromatin dynamics and co-regulating inflammation-related genes with NF-KB.

This study shows JC polyomavirus uses epigenetic mimicry to alter nuclear architecture, enabling viral replication and persistence.

The paper shows how mechanical forces from epithelial and mesenchymal compartments coordinate cell shape and fate to form tissue architecture during hair follicle development.