Céline Labouesse

HydroMEA: A 3D Hydrogel Based Microfluidic Device to Study Electrophysiology for Myelinated Nerve-on-Chip

The paper introduces hydroMEA, a 3D hydrogel-based microfluidic device that enables real-time electrophysiological measurements of myelinated nerve-on-chip systems using human iPSC-derived neurons and Schwann cells.

Intrinsic mechanotransduction during apical constriction licenses lineage competence in pluripotent stem cells

This study shows that mechanical forces during epithelialization in pluripotent stem cells drive nuclear changes that prime neuroectodermal lineage commitment.

Tunable bicontinuous macroporous cell culture scaffolds via kinetically controlled phase separation

This paper develops tunable macroporous hydrogels via phase separation for cell culture, showing improved cell spreading and migration in porous systems.

Cell-matrix force transmission regulates the loss of naïve pluripotency in mouse embryonic stem cells.

This study shows that cell-matrix forces increase during the loss of naive pluripotency in mESCs and are required for this process.