Author

Antony Lechner

Centre National de la Recherche ScientifiqueORCID 0000-0003-2904-3584Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Assay:metagenomics· 1

Frequent Co-Authors

Philippe Wolff· 2 shared Bibek Hamal· 1 shared Bruno P. KlaholziD· 1 shared Charles BarchetiD· 1 shared Ella Bellenberg· 1 shared Isabelle Hazemann· 1 shared Jan Felix Dalwigk· 1 shared Jannick Schicktanz· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Philippe Wolff

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJul 17, 2026

Human 28S rRNA analysed by state-of-the-art oligonucleotide mass spectrometry: benchmarking current capabilities and a call to action for MS-Seq

Jannick Schicktanz, Ying Qi, Junzhou Wu…·Stefanie Kaiser

The paper benchmarks MS-Seq for human 28S rRNA analysis, showing reproducible results across platforms but highlighting gaps in coverage and ambiguity.

DOI 10.64898/2026.07.17.739151

humanmetagenomics

𝕏 PostBluesky

BiochemistrybioRxivPreprintNov 23, 2023

Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical modifications and ions in RNA

Samuel Holvec, Charles Barchet, Antony Lechner…·Bruno P. Klaholz

The paper presents a 1.9 Å cryo-EM structure of the human 80S ribosome, revealing new rRNA modifications and ions, and their roles in RNA architecture and function.

DOI 10.1101/2023.11.23.568509

humancryo-EM

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