Junzhou Wu

Ion-Pair-Free Capillary HILIC-MS for Sensitive Nucleic Acid Analysis and RNA Modification Mapping

This paper develops an ion-pair-free capillary HILIC-MS workflow for RNA modification mapping, enabling sensitive detection of modifications in tRNAs and rRNAs without contaminating the MS system.

Human 28S rRNA analysed by state-of-the-art oligonucleotide mass spectrometry: benchmarking current capabilities and a call to action for MS-Seq

The paper benchmarks MS-Seq for human 28S rRNA analysis, showing reproducible results across platforms but highlighting gaps in coverage and ambiguity.

tRNA modification profiling reveals epitranscriptome regulatory networks in Pseudomonas aeruginosa

The paper profiles tRNA modifications in Pseudomonas aeruginosa to uncover regulatory networks and validate gene annotations.

Genome-wide mapping of 5'-aldehyde terminus induced by reactive oxygen species

The paper develops a method to map 5'-aldehyde termini in DNA at single-nucleotide resolution, revealing a preference for adenine bases and linking these lesions to genomic features and chromatin accessibility.