Human 28S rRNA analysed by state-of-the-art oligonucleotide mass spectrometry: benchmarking current capabilities and a call to action for MS-Seq
Jannick Schicktanz, Ying Qi, Junzhou Wu, Bibek Hamal, Antony Lechner, Sam Wein, Oskar Knittelfelder, Nur Yeşiltaç-Tosun, Jan Felix Dalwigk, Katharina Hoja, Leona A. Rusling, Sofia Obersteiner, Ella Bellenberg, Kira Kerkhoff, Michael S. DeMott, , Stefanie Kaiser
The paper benchmarks MS-Seq for human 28S rRNA analysis, showing reproducible results across platforms but highlighting gaps in coverage and ambiguity.
bioRxiv · Jul 17, 2026 · PreprintMolecular Biology