Author

Penelope D. Ruiz

Rockefeller UniversityORCID 0000-0003-2904-5432Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Agata SmogorzewskaiD· 1 shared Brooke A. ContiiD· 1 shared Cayla BrotoniD· 1 shared Francis P. LachiD· 1 shared Gregory A. HamiltoniD· 1 shared Kenny Q. YeiD· 1 shared Matthew J. GambleiD· 1 shared Molly C. Kottemann· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Agata SmogorzewskaORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintFeb 7, 2025

Acetylation of histone H2B on lysine 120 regulates BRD4 binding to intergenic enhancers

Gregory A. Hamilton, Penelope D. Ruiz, Kenny Q. Ye, Matthew J. Gamble

The paper identifies H2BK120ac as critical for BRD4 recruitment to intergenic enhancers and shows its role in BRD4-NUT-driven oncogenesis.

3 citations

𝕏 PostBluesky

Molecular BiologyNature CommunicationsPeer-reviewedMar 2, 2024

RTF2 controls replication repriming and ribonucleotide excision at the replisome

Brooke A. Conti, Penelope D. Ruiz, Cayla Broton…·Agata Smogorzewska

This study shows RTF2 regulates replication repriming and ribonucleotide excision at the replisome, ensuring efficient replication restart and preventing replication stress.

8 citations

humanDNA methylation

𝕏 PostBluesky