Author

Michela Saviana

Virginia Commonwealth UniversityORCID 0000-0003-2915-8752Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metagenomics· 1

Frequent Co-Authors

Daniel del Valle MoralesiD· 2 shared Giovanni NigitaiD· 2 shared Giulia RomanoiD· 2 shared Mario AcunzoiD· 2 shared Patrick S. Nana-SinkamiD· 2 shared Alessandro La FerlitaiD· 1 shared Howard Y. LiiD· 1 shared Lavender Micalo· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Daniel del Valle MoralesORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 3, 2026

A multi-omics approach to identify the impact of miR-411ed on NSCLC TKI resistance

Daniel del Valle Morales, Giulia Romano, Michela Saviana…·Mario Acunzo

This study uses a multi-omics approach to show miR-411ed enhances Osimertinib efficacy in TKI-resistant NSCLC by targeting STAT3 and altering interferon and ERK/MAPK pathways.

DOI 10.64898/2026.03.31.715663

humanbulk RNA-seq

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Molecular BiologyScientific ReportsPeer-reviewedNov 12, 2024

METTL3 alters capping enzyme expression and its activity on ribosomal proteins

Daniel del Valle Morales, Giulia Romano, Giovanni Nigita…·Mario Acunzo

This study investigates how METTL3 regulates RNGTT expression and activity, finding that METTL3 knockdown destabilizes RNGTT mRNA and reduces protein expression, with downstream effects on ribosomal protein capping and mTOR pathway disruption.

5 citations

metagenomicsstatistical model

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