Christopher S. Fry

Disrupted FAP-satellite cell communication contribute to maladaptive muscle remodeling in older women

This study identifies altered FAP-satellite cell communication and impaired myogenic function in older women during recovery from disuse atrophy, contributing to poor muscle remodeling.

Skeletal Muscle Stem Cell-Derived Myonuclei Adopt Divergent Terminal Transcriptional States in Adult and Aged Muscle In Response to a Hypertrophic Stimulus

The paper identifies age-related differences in the transcriptional states of MuSC-derived myonuclei in response to mechanical overload.

Muscle mass and denervation explain variability in maximal power and rapid force across the adult female lifespan

This study examines how muscle mass and denervation affect maximal power and rapid force in adult females across their lifespan.

Transient MYC Mimicking the Exercise Response Orchestrates Multifaceted Skeletal Muscle Adaptations

The paper shows that transient MYC activation in skeletal muscle mimics exercise-induced adaptations, leading to hypertrophy, metabolic changes, and fiber type shifts.

Resistance Exercise and Mechanical Overload Upregulate Vimentin for Skeletal Muscle Remodeling

The paper investigates how resistance exercise and mechanical overload upregulate vimentin in skeletal muscle, linking it to hypertrophy and regeneration.

The 24-Hour Time Course of Integrated Molecular Responses to Resistance Exercise in Human Skeletal Muscle Implicates MYC as a Hypertrophic Regulator That is Sufficient for Growth

This study maps the 24-hour molecular response to resistance exercise in human muscle, identifying MYC as a key regulator of hypertrophy and mRNA levels.