Author

Michael C. Ostrowski

Medical University of South CarolinaORCID 0000-0003-2948-6297Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Julia E. Lefler· 2 shared Sudarshana M. SharmaiD· 2 shared Adele M. Snowman· 1 shared Andrew A. PieperiD· 1 shared Bindu Diana PauliD· 1 shared Blake Eason HildrethiD· 1 shared Bobby ThomasiD· 1 shared Brittany R. CountsiD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersNeuroscience

Julia E. Lefler

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 1, 2025

Pancreatic Cancer Induces Population-Specific Switching of Myosin Isoforms and Discrete Activation of Cachexia Genes in Skeletal Muscle Myocytes

Brittany R. Counts, Sephora Jean, Omnia U. Gaafer…·Teresa A. Zimmers

This study identifies population-specific transcriptional changes in skeletal muscle myonuclei during pancreatic cancer cachexia, revealing distinct gene activation patterns rather than uniform upregulation of cachexia mediators.

DOI 10.1101/2025.09.01.673500

humanscRNA-seq

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NeurosciencebioRxivPreprintJun 4, 2025

Biliverdin Reductase A is a major determinant of neuroprotective Nrf2 signaling

Chirag Vasavda, Ruchita Kothari, Navneet Ammal Kaidery…·Bindu Diana Paul

This paper identifies a novel non-enzymatic role for BVRA in modulating Nrf2 signaling, revealing its importance in neuroprotection and potential as a therapeutic target for neurodegenerative diseases.

DOI 10.1101/2025.06.04.657936

humanstatistical model

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GenomicsbioRxivPreprintFeb 19, 2020

Redundant function of Ets1 and Ets2 in regulating M-phase progression in post-natal angiogenesis

Sankha Ghosh, Catherine B. MarElia, Blake Eason Hildreth…·Michael C. Ostrowski

This study shows that ETS1 and ETS2 redundantly regulate M-phase progression and cell survival in post-natal angiogenesis by controlling G2/M regulators and anti-apoptotic genes.

4 citations

mouseexperimental assay

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