Biliverdin Reductase A is a major determinant of neuroprotective Nrf2 signaling
Chirag Vasavda, Ruchita Kothari, Navneet Ammal Kaidery, Suwarna Chakraborty, Sunil Jamuna Tripathi, Ryan S. Dhindsa, Samaneh Saberi, Julia E. Lefler, Priyanka Kothari, Kalyani Chaubey, Cristina Ricco, Adele M. Snowman, Michael C. Ostrowski, Eugenio Barone, Lakshminarayan M. Iyer, , Bindu Diana Paul
This paper identifies a novel non-enzymatic role for BVRA in modulating Nrf2 signaling, revealing its importance in neuroprotection and potential as a therapeutic target for neurodegenerative diseases.
bioRxiv · Jun 4, 2025 · PreprintNeuroscience