Author

Ruchita Kothari

Johns Hopkins UniversityORCID 0000-0002-9575-6200Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Adele M. Snowman· 2 shared Bindu Diana PauliD· 2 shared Chirag VasavdaiD· 2 shared Cristina RiccoiD· 2 shared Eugenio BaroneiD· 2 shared Ryan S. DhindsaiD· 2 shared Solomon H. SnyderiD· 2 shared Ami A. ShahiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersNeuroscience

Adele M. Snowman

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3 papers

Recent·Most cited

A mast cell receptor is associated with fibrosis and itch in systemic sclerosis

Ruchita Kothari, Daniel Capuzzi, Collin B. Kilgore, Hyun Jong Oh, Saloni Patel, Anjana Srikumar, Gwen Leatherman, Ami A. Shah, Jun Kang, Xinzhong P Dong

This study identifies Mrgprb2 as a mast cell receptor involved in fibrosis and itch in systemic sclerosis using a mouse model and human tissue analysis.

bioRxiv · Oct 10, 2026 · PreprintImmunology

Biliverdin Reductase A is a major determinant of neuroprotective Nrf2 signaling

Chirag Vasavda, Ruchita Kothari, Navneet Ammal Kaidery, Suwarna Chakraborty, Sunil Jamuna Tripathi, Ryan S. Dhindsa, Samaneh Saberi, Julia E. Lefler, Priyanka Kothari, Kalyani Chaubey, Cristina Ricco, Adele M. Snowman, Michael C. Ostrowski, Eugenio Barone, Lakshminarayan M. Iyer, , Bindu Diana Paul

This paper identifies a novel non-enzymatic role for BVRA in modulating Nrf2 signaling, revealing its importance in neuroprotection and potential as a therapeutic target for neurodegenerative diseases.

bioRxiv · Jun 4, 2025 · PreprintNeuroscience

Biliverdin reductase bridges focal adhesion kinase to Src to modulate synaptic signaling

Chirag Vasavda, Evan R. Semenza, Jason Liew, Ruchita Kothari, Ryan S. Dhindsa, Shruthi Shanmukha, Anthony L. Lin, Robert A. Tokhunts, Cristina Ricco, Adele M. Snowman, Lauren K. Albacarys, Francesco Pastore, Cristian Ripoli, Claudio Grassi, Eugenio Barone, , Solomon H. Snyder

This study identifies biliverdin reductase (BVR) as a bridge between FAK/Pyk2 and Src, showing its role in synaptic signaling and learning/memory deficits in BVR-null mice.

Science Signaling · May 10, 2022Peer-reviewedNeuroscience