Hugh O’Neill

This study uses SANS and molecular dynamics to show that Cel7A adopts distinct conformations when bound to cellulose compared to free solution, highlighting dynamic structural changes during catalysis.

This study shows that the N-terminal domain of Arabidopsis CC1 undergoes liquid-liquid phase separation under stress conditions, recruiting tubulin and accelerating microtubule polymerization.

This paper uses SAXS and SANS to analyze conformational changes in RNA:RNA complexes, validating and improving AlphaFold 3 predictions through isotope labeling and contrast matching.