Author

Edgar Jost

Universitätsklinikum AachenORCID 0000-0003-2998-2450Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Wolfgang WagneriD· 2 shared Annamarija Raic· 1 shared Chao-Chung Kuo· 1 shared Chao‐Chung KuoiD· 1 shared Fabio TicconiiD· 1 shared Florian KraftiD· 1 shared Ivan G. CostaiD· 1 shared Joana Frobel· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Wolfgang WagnerORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 9, 2026

Aberrant DNA methylation is co-regulated across the genome in leukemia and other types of cancer

Monica Varona Baranda, Sven Liesenfelder, Florian Kraft…·Wolfgang Wagner

This study identifies co-regulated DNA methylation patterns in leukemia and shows their presence in other cancer types, suggesting non-random, network-based epigenetic regulation.

DOI 10.64898/2026.06.05.729844

humanDNA methylation

𝕏 PostBluesky

Cell BiologybioRxivPreprintMay 9, 2018

Variants of DNMT3A cause transcript-specific DNA methylation patterns and affect hematopoietic differentiation

Tanja Božić, Joana Frobel, Annamarija Raic…·Wolfgang Wagner

This study shows that specific DNMT3A transcripts have distinct epigenetic and functional effects on hematopoietic differentiation and are linked to AML outcomes.

DOI 10.1101/318188

humanDNA methylation

𝕏 PostBluesky