Author

Sven Liesenfelder

RWTH Aachen UniversityORCID 0009-0007-8503-3344Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Juan-Felipe Perez-CorreaiD· 2 shared Monica Varona Baranda· 2 shared Wolfgang WagneriD· 2 shared Argyris PapantonisiD· 1 shared Athanasia MiziiD· 1 shared Chao‐Chung KuoiD· 1 shared Edgar JostiD· 1 shared Florian KraftiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Juan-Felipe Perez-CorreaORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 9, 2026

Aberrant DNA methylation is co-regulated across the genome in leukemia and other types of cancer

Monica Varona Baranda, Sven Liesenfelder, Florian Kraft…·Wolfgang Wagner

This study identifies co-regulated DNA methylation patterns in leukemia and shows their presence in other cancer types, suggesting non-random, network-based epigenetic regulation.

DOI 10.64898/2026.06.05.729844

humanDNA methylation

𝕏 PostBluesky

GeneticsNature AgingPeer-reviewedMar 24, 2025

Epigenetic editing at individual age-associated CpGs affects the genome-wide epigenetic aging landscape

Sven Liesenfelder, Mohamed H. Elsafi Mabrouk, Jessica Iliescu…·Wolfgang Wagner

This study shows that epigenetic editing at age-associated CpGs can modulate the epigenetic aging landscape, affecting epigenetic clocks and inducing non-random bystander modifications.

38 citationstop 1%

humanDNA methylation

𝕏 PostBluesky