GenomicsGenome biologyPeer-reviewed
Amplification-free long read sequencing reveals unforeseen CRISPR-Cas9 off-target activity
Ida Höijer, Josefin Johansson, Sanna Gudmundsson…·Adam Ameur
The paper introduces amplification-free long-read sequencing protocols to detect CRISPR-Cas9 off-target binding sites, identifying many previously undetected sites that are not predicted by existing software.
63 citations