Author

Aaron Chan

University of Illinois Urbana-ChampaignORCID 0000-0003-3000-4275Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 1 Approach:deep learning· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:metagenomics· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Amar D. ParvateiD· 1 shared Angad P. MehtaiD· 1 shared August GeorgeiD· 1 shared Co D. QuachiD· 1 shared Connah JohnsoniD· 1 shared D. H. Kim· 1 shared Emad TajkhorshidiD· 1 shared Erin N. Lessie· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperSystems Biology

Amar D. ParvateORCID

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2 papers

Recent·Most cited

Systems BiologyBiophysical JournalPeer-reviewedAug 26, 2026

Spatiotemporal 4D Whole-cell Modeling of a Minimal Autotroph Reveals Central Carbon Metabolism Regulated Locally by Protein Megacomplexes via Post-translational Modifications under Light Disturbance

Connah Johnson, Aaron Chan, Jordan C. Rozum…·Margaret S. Cheung

The paper develops a 4D whole-cell model of Prochlorococcus marinus MED4 to show how spatial organization and redox PTMs regulate carbon fixation under light disturbance.

1 citation

C. elegansproteomics

𝕏 PostBluesky

BiophysicsNature CommunicationsPeer-reviewedAug 3, 2025

Voltage Sensor Conformations Induced by LQTS-associated Mutations in hERG Potassium Channels

Aaron N. Chan, Co D. Quach, Lucas J. Handlin…·Gucan Dai

The paper identifies intermediate voltage-sensor conformations in hERG channels caused by LQTS-associated mutations using FLIM, tmFRET, and MD simulations.

5 citations

humanfluorescence / live-cell microscopy

𝕏 PostBluesky