Author

August George

Pacific Northwest National LaboratoryORCID 0000-0001-7876-4359Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Systems Biology· 2 Bioinformatics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:proteomics· 3 Approach:statistical model· 3 Organism:bacteria (other)· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Approach:large language model· 1

Frequent Co-Authors

Margaret S. CheungiD· 3 shared Paul RigoriD· 3 shared Daniel Mejı́a-Rodrı́gueziD· 2 shared Jordan C. RozumiD· 2 shared Lindsey N Anderson· 2 shared Pavlo BohutskyiiD· 2 shared Ruonan WuiD· 2 shared Song Feng· 2 shared

Activity by Year

2026-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

Margaret S. CheungORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cyanophage CP12 Rewires Host Carbon Regulation through Interface Remodeling and Redox Buffering

Scott Widmann, Ruonan Wu, Malio Nelson, Daniel Mejı́a-Rodrı́guez, Suman Samantray, Reece Neff, Song Feng, Xiaolu Li, Jordan C. Rozum, August George, Paul Rigor, Pavlo Bohutskyi, Noelani R Boise, Ho Shin Kim, Lindsey N Anderson, , Margaret S. Cheung

This study investigates how cyanophage CP12 modulates host carbon regulation by remodeling interfaces and buffering redox changes during infection.

bioRxiv · Sep 11, 2026 · PreprintMicrobiology

Spatiotemporal 4D Whole-cell Modeling of a Minimal Autotroph Reveals Central Carbon Metabolism Regulated Locally by Protein Megacomplexes via Post-translational Modifications under Light Disturbance

Connah Johnson, Aaron Chan, Jordan C. Rozum, August George, Amar D. Parvate, Pavlo Bohutskyi, D. H. Kim, Song Feng, Zachary Johnson, Natalie Sadler, Marci Garcia, Xiaolu Li, Jesse B. Trejo, Ruonan Wu, William Sineath, , Margaret S. Cheung

The paper develops a 4D whole-cell model of Prochlorococcus marinus MED4 to show how spatial organization and redox PTMs regulate carbon fixation under light disturbance.

Biophysical Journal · Aug 26, 2026Peer-reviewedSystems Biology

ChatGEM: An Agentic Architecture Enabling Interactive Simulation of Genome-Scale Metabolic Models

Niaz Bahar Chowdhury, August George, Sumit Purohit, Angela Contolesi, Erin Bredeweg, Jeffrey J. Czajka, Kelly G. Stratton, Yuqian Gao, Molly Stephenson, Joshua R. Elmore, Allan Scott, Damon T. Leach, Abby Jerger, Teresa Lemmon, Paul Piehowski, , Jaydeep P. Bardhan

ChatGEM enables interactive simulation of genome-scale metabolic models via natural language, improving performance and reducing execution time for complex tasks.

bioRxiv · Jul 21, 2026 · PreprintSystems Biology

An LLM-driven pipeline for proteomics-based detection and structural modeling of post-translational modifications

August George, Daniel Mejı́a-Rodrı́guez, Xiaolu Li, Paul Rigor, Margaret S. Cheung, Aivett Bilbao

The paper introduces an LLM-driven pipeline for detecting and structurally modeling post-translational modifications using proteomics data.

bioRxiv · May 6, 2026 · PreprintBioinformatics