Author

Andrew A. Leal

Boston UniversityORCID 0000-0003-3020-9131Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Andrés A. Quiñones-MolinaiD· 1 shared Andrew J. HendersoniD· 1 shared Daniel L. Bryant· 1 shared Ignaty LeshchineriD· 1 shared Joseph B McWhirteriD· 1 shared Manish SagariD· 1 shared Maria AndradeiD· 1 shared Melissa Beth HerringiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Andrés A. Quiñones-MolinaORCID

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1 paper

Recent·Most cited

MicrobiologybioRxivPreprintApr 27, 2026

Bloom syndrome helicase is required for efficient HIV-1 reverse transcription in macrophages

Andrew A. Leal, Samantha Tafrate, Xianbao He…·Andrew J. Henderson

This study identifies Bloom syndrome helicase (BLM) as a host factor that promotes HIV-1 reverse transcription and integration in macrophages through CRISPR screening and functional assays.

DOI 10.64898/2026.04.26.720894

humangenetic perturbation / CRISPR

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