Author

Samantha Tafrate

Boston Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrés A. Quiñones-MolinaiD· 1 shared Andrew A. LealiD· 1 shared Andrew J. HendersoniD· 1 shared Brickley Littell· 1 shared Daniel L. Bryant· 1 shared Emily R. Mynar· 1 shared Ignaty LeshchineriD· 1 shared Jon P. Girard· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Andrés A. Quiñones-MolinaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

An Aurora Kinase-Dependent Role for Vif in Regulating HIV-1-Induced Cell-Cell Fusion

Samantha Tafrate, Brickley Littell, Jon P. Girard, Emily R. Mynar, Madeline K Carr, Markus Thali, Menelaos Symeonides

This study shows Vif regulates HIV-1-induced cell-cell fusion through Aurora kinase signaling, with Ezrin as a downstream effector.

bioRxiv · Jun 16, 2026 · PreprintCell Biology

Bloom syndrome helicase is required for efficient HIV-1 reverse transcription in macrophages

Andrew A. Leal, Samantha Tafrate, Xianbao He, Daniel L. Bryant, Melissa Beth Herring, Maria Andrade, Joseph B McWhirter, Andrés A. Quiñones-Molina, Suryaram Gummuluru, Manish Sagar, Rachel Litman Flynn, Ignaty Leshchiner, Andrew J. Henderson

This study identifies Bloom syndrome helicase (BLM) as a host factor that promotes HIV-1 reverse transcription and integration in macrophages through CRISPR screening and functional assays.

bioRxiv · Apr 27, 2026 · PreprintMicrobiology