Rockwell P. Tang

This paper develops a physics-informed neural network to rapidly estimate vascular and tissue dynamics from laser speckle contrast imaging data without ground-truth labels.

This study shows that visual gamma stimulation increases low-frequency blood flow oscillations in multiple cortical regions of mice, with effects lasting beyond 24 hours.

This study investigates slow speckle dynamics (SSD) in vivo to assess cellular metabolic activity using laser speckle contrast imaging, finding SSD correlates with metabolic processes and vascular dynamics.

The paper shows that hemodynamic responses in the cortex are influenced by neuromodulators like norepinephrine, with distinct impulse response functions for different neuromodulatory signals.

The paper describes a widefield in vivo imaging system for mesoscopic brain imaging, capable of capturing fluorescent and reflectance signals, and demonstrates its use in awake mice.