John Jiang

Visual gamma stimulation causes prolonged enhancement of low-frequency blood flow oscillations across cortical regions in mice

This study shows that visual gamma stimulation increases low-frequency blood flow oscillations in multiple cortical regions of mice, with effects lasting beyond 24 hours.

Mapping Slow Speckle Dynamics to Probe Cellular Metabolic Activity In Vivo using Laser Speckle Contrast Imaging

This study investigates slow speckle dynamics (SSD) in vivo to assess cellular metabolic activity using laser speckle contrast imaging, finding SSD correlates with metabolic processes and vascular dynamics.

Optical coherence tomography enables longitudinal evaluation of cell graft-directed remodeling in stroke lesions

This study uses OCT to track changes in stroke lesions after cell grafting, finding that lesion contraction and graft survival are influenced by lesion size and severity.

Neurovascular Impulse Response Function (IRF) during spontaneous activity differentially reflects intrinsic neuromodulation across cortical regions

The paper shows that hemodynamic responses in the cortex are influenced by neuromodulators like norepinephrine, with distinct impulse response functions for different neuromodulatory signals.

Widefield in vivo imaging system with two fluorescence and two reflectance channels, a single sCMOS detector, and shielded illumination

The paper describes a widefield in vivo imaging system for mesoscopic brain imaging, capable of capturing fluorescent and reflectance signals, and demonstrates its use in awake mice.

Visual stimulation drives retinotopic acetylcholine release in the mouse visual cortex

The paper shows visual stimulation causes retinotopic acetylcholine release in the mouse visual cortex, indicating organized cholinergic signaling.

High Throughput Detection of Capillary Stalling Events with Bessel Beam Two-Photon Microscopy

This study develops a Bessel beam two-photon microscope to detect capillary stalling events in stroke models, showing increased stalling beyond the acute phase.