Developmental BiologybioRxivPreprint
Expansion of Ventral Foregut Primes the Enhancer Landscape for Organ Specific Differentiation
Yan Fung Wong, Yatendra Kumar, Martin Proks…·Joshua M. Brickman
The paper shows that cell proliferation in human embryonic stem cell-derived endodermal progenitors primes enhancer landscapes for organ-specific differentiation by modulating chromatin accessibility and enhancer decommissioning.
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