Transcriptional Heterogeneity and Cell Cycle Regulation as Central Determinants of Primitive Endoderm Priming.
Marta Perera, Silas Boye Nissen, Martin Proks, Sara Pozzi, Rita S. Monteiro, Ala Trusina, Joshua M. Brickman
The paper investigates how cell cycle regulation influences transcriptional heterogeneity and lineage priming in embryonic stem cells differentiating into primitive endoderm.
eLife · Aug 15, 2022Peer-reviewedDevelopmental Biology