Author
Translational Research InstituteORCID 0000-0003-3092-8283Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Parastoo Shahrouzi, Youness Azimzade, Wioletta Brankiewicz…·Pascal H. G. Duijf
This study identifies the loss of chromosome 13q14.2 as a key driver of breast cancer pathogenesis and drug response, showing its impact on tumor survival, cell cycle, and treatment susceptibility.
Paras Jain, Ramanarayanan Kizhuttil, Madhav B Nair…·Mohit Kumar Jolly
The paper models the dynamics of E-M heterogeneity in breast cancer cells, finding that cell-state transitions, not growth differences, are essential for explaining observed population dynamics.
Jessica J. King, Cameron W. Evans, Ulrich D. Kadolsky…·Nicole M. Smith
The paper introduces a new multiplexed single-cell sequencing method to identify metastable cell states during EMT and shows G-quadruplex DNA stabilization can inhibit EMT.
Paras Jain, Sugandha Bhatia, Erik W. Thompson, Mohit Kumar Jolly
The paper models phenotypic switching in cancer cells to explain spontaneous epithelial-mesenchymal heterogeneity through stochastic SNAIL partitioning during cell division.