Canonical NOTCH signaling controls the early progenitor state and emergence of the medullary epithelial lineage in fetal thymus development.
Dong Liu, Anastasia I. Kousa, Kathy E. O’Neill, Paul Rouse, Martyna C. Popis, Alison Farley, Simon R. Tomlinson, Svetlana Ulyanchenko, François Guillemot, Philip Allan Seymour, Mette Christine Jørgensen, Palle Serup, Ute Koch, Freddy Radtke, Clare C. Blackburn
This study shows NOTCH signaling regulates early thymic epithelial progenitor cells and mTEC lineage emergence during fetal thymus development.
Development · Jan 1, 2020Peer-reviewedDevelopmental Biology