Author

Sara Badodi

Queen Mary University of LondonORCID 0000-0002-8407-8336Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Silvia MarinoiD· 2 shared Andrew W. McEvoyiD· 1 shared Ashirwad MerveiD· 1 shared Benjamin DraperiD· 1 shared Charles A. MeiniD· 1 shared Dimitris Paraskevopoulos· 1 shared Edward McKintosh· 1 shared Gerald John McKennaiD· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Silvia MarinoORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 14, 2024

Modelling medulloblastoma pathogenesis and treatment in human cerebellar organoids.

Thomas Willott, James G Nicholson, Yunchen Xiao…·Silvia Marino

This study generates human cerebellar organoids to model medulloblastoma subgroups G3 and G4, showing their ability to sustain tumor growth and respond to anti-tumour compounds.

2 citations

humanorganoid / primary culture

NeurosciencebioRxivPreprintMar 4, 2024

The inflammatory micro-environment induced by targeted CNS radiotherapy is underpinned by disruption of DNA methylation

Thomas O Millner, Pratistha Panday, Yu Xiao…·Silvia Marino

This study shows that targeted CNS radiotherapy disrupts DNA methylation and induces neuroinflammation through epigenetic changes in brain tissue and cerebral organoids.

DOI 10.1101/2024.03.04.581366

humanbulk RNA-seq

Developmental BiologyeLifePeer-reviewedOct 1, 2020

Myogenin is an Essential Regulator of Adult Myofibre Growth and Muscle Stem Cell Homeostasis

Massimo Ganassi, Sara Badodi, Kees Wanders…·Simon M. Hughes

This study shows that Myogenin regulates adult muscle fibre growth and stem cell homeostasis by affecting myonuclear domain size, MuSC activation, and mTORC1 signaling.

152 citationstop 2%

zebrafishexperimental assay