Lindsay B. Case

This study identifies GAB1 as a regulator of EGFR condensate size and composition through phosphorylation-dependent mechanisms and PH domain-mediated oligomerization.

This study uses AI to design protein fragments that regulate biomolecular condensates, showing success in multiple targets and revealing new interaction mechanisms.

This study shows kinase condensates enhance autophosphorylation by concentrating kinases and ATP, revealing phase separation as a mechanism to activate kinase signaling.