Author

Hidenori Homma

Institute of Science TokyoORCID 0000-0003-3175-7463Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Hikari TanakaiD· 2 shared Hitoshi OkazawaiD· 2 shared Kyota FujitaiD· 2 shared Yuki YoshiokaiD· 2 shared Aiko Ishiki· 1 shared Albert R. La SpadaiD· 1 shared Atsushi IwataiD· 1 shared Gen SobueiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

Hikari TanakaORCID

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2 papers

Recent·Most cited

NeuroscienceMolecular PsychiatryPeer-reviewedSep 12, 2026

PQBP1-dependent alternative RNA splicing underlies high calorie diet-induced cognitive impairment

Yong Huang, Hidenori Homma, Yuki Yoshioka…·Hitoshi Okazawa

This study identifies PQBP1-dependent alternative RNA splicing as a mechanism underlying HFD-induced cognitive impairment through effects on synaptic vesicle release.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintJun 12, 2025

Aβ-HMGB1 complex is a pathogenic molecule at the advanced stage of Alzheimer's disease

Hikari Tanaka, Hidenori Homma, Yuki Yoshioka…·Hitoshi Okazawa

This study identifies the Aβ-HMGB1 complex as a pathogenic factor in advanced Alzheimer's disease, showing it causes neuronal damage and that targeting HMGB1 improves symptoms in mouse models.

DOI 10.1101/2025.06.12.659430

humanmouse

𝕏 PostBluesky