Edmund Au

The paper identifies a neuron type-specific microexon in Ank3/ankyrin-G that modulates calcium activity and neuronal excitability through alternative splicing.

The paper uses single-cell transcriptomes to reverse engineer splicing-regulatory networks specific to and orthogonal of neuron types, identifying key RNA-binding proteins and regulatory modules.

The paper develops a method to analyze synaptic features of cortical interneurons, revealing synaptic heterogeneity and distinct strategies in inhibitory coverage.

This study identifies St18 as a transcriptional determinant specifying projection neuron identity in the MGE lineage and shows its role in regulating migration and morphology of GPe neurons.

This study shows that loss of clustered protocadherin diversity disrupts the spatial arrangement of cortical interneuron subclasses.