Author

Gregg W. Crabtree

Mortimer B. Zuckerman Mind Brain Behavior InstituteORCID 0000-0002-0079-2277Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Joseph A. GogosiD· 3 shared Anastasia DiamantopoulouiD· 1 shared Angeliki MelaiD· 1 shared Anna MolotkovaiD· 1 shared Atsushi TakataiD· 1 shared Bin XuiD· 1 shared Chaolin ZhangiD· 1 shared Chia‐Yuan ChangiD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersNeuroscience

Joseph A. GogosORCID

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3 papers

Recent·Most cited

Cortical assembloids support the development of fast-spiking human PVALB+ cortical interneurons and uncover schizophrenia-associated defects

Ryan M. Walsh, Gregg W. Crabtree, Kriti Kalpana, Luz Jubierre, So Yeon Koo, Gabriele Ciceri, Joseph A. Gogos, Ilya Kruglikov, Lorenz Studer

The paper develops a cortical assembloid system to study human PVALB+ interneuron development and identifies schizophrenia-associated defects in their migration and molecular profiles.

bioRxiv · Nov 26, 2024 · PreprintNeuroscience

Vascular-Derived SPARC and SerpinE1 Regulate Interneuron Tangential Migration and Accelerate Functional Maturation of Human Stem Cell-Derived Interneurons

Matthieu Genestine, Daisy Ambriz, Gregg W. Crabtree, Patrick D. Dummer, Anna Molotkova, Michael Quintero, Angeliki Mela, Saptarshi Biswas, Huijuan Feng, Chaolin Zhang, Peter Canoll, Gunnar Hargus, Dritan Agalliu, Joseph A. Gogos, Edmund Au

eLife · Apr 27, 2021Peer-reviewedNeuroscience

Recapitulation and reversal of schizophrenia-related phenotypes in Setd1a-deficient mice

Jun Mukai, Enrico Cannavò, Gregg W. Crabtree, Ziyi Sun, Anastasia Diamantopoulou, Pratibha Thakur, Chia‐Yuan Chang, Yifei Cai, Stavros Lomvardas, Atsushi Takata, Bin Xu, Joseph A. Gogos

This study shows that Setd1a-deficient mice exhibit schizophrenia-like phenotypes, which can be reversed by restoring Setd1a expression or inhibiting LSD1.

Neuron · Oct 9, 2019Peer-reviewedNeuroscience