Author

Alison Pattie

University of Edinburgh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Neuroscience· 4 Genetics· 2 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 7 Approach:statistical model· 7 Research Focus:differential expression· 4 Assay:DNA methylation· 3 Research Focus:benchmarking· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Ian J. DearyiD· 7 shared Janie CorleyiD· 5 shared Riccardo Emilio MarioniiD· 5 shared Sarah E. HarrisiD· 5 shared Joanna Marguerite WardlawiD· 4 shared John M. StarriD· 4 shared Maria del Carmen Valdés HernándeziD· 4 shared Mark E. BastiniD· 4 shared

Activity by Year

2017-2020 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

7 shared papersNeuroscience

Ian J. DearyORCID

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Plasma lipid and liporotein biomarkers in LBC1936: Do they predict general cognitive ability and brain structure?

Sarah E. Harris, Stuart James Ritchie, Gonçalo dos Santos Correia, Beatriz Jiménez, Chloe Fawns‐Ritchie, Alison Pattie, Janie Corley, Susana Muñoz Maniega, Maria del Carmen Valdés Hernández, John M. Starr, David Hill, Paul B. Wren, Mark E. Bastin, Matthew R. Lewis, Joanna Marguerite Wardlaw, Ian J. Deary

This study identifies lipid biomarkers associated with brain structure but not cognitive ability in older adults using metabolomic data from the LBC1936 cohort.

bioRxiv · Jul 9, 2020 · PreprintNeuroscience

An epigenetic predictor of death captures multi-modal measures of brain health

Robert Francis Hillary, Anna J. Stevenson, Simon R. Cox, Daniel L. McCartney, Sarah E. Harris, Anne Seeboth, Jonathan Higham, Duncan Sproul, Adele M. Taylor, Paul H. Redmond, Janie Corley, Alison Pattie, María del C. Valdés Hernández, Susana Muñoz Maniega, Mark E. Bastin, , Riccardo Emilio Marioni

This paper introduces DNAm GrimAge, an epigenetic clock that predicts mortality and is associated with multiple brain health measures in older adults.

Molecular Psychiatry · Dec 3, 2019Peer-reviewedNeuroscience

Neurology-related protein biomarkers are associated with general fluid cognitive ability and brain volume in older age

Sarah E. Harris, Simon R. Cox, Steven Bell, Riccardo Emilio Marioni, Bram Peter Prins, Alison Pattie, Janie Corley, Susana Muñoz Maniega, Maria del Carmen Valdés Hernández, Zoë Morris, Sally John, Paola G. Bronson, Elliot M. Tucker–Drob, John M. Starr, Mark E. Bastin, , Ian J. Deary

This study identifies neurology-related proteins in plasma associated with cognitive ability and brain volume in older adults, with partial mediation by brain volume.

bioRxiv · Jul 4, 2019 · PreprintNeuroscience

Age and mortality associated DNA methylation patterns on the X-chromosome in male and female samples

Shuxia Li, Jesper Lund, Jan Baumbach, Kaare Christensen, Jonas Mengel‐From, Weilong Li, Afsaneh Mohammadnejad, Alison Pattie, Riccardo Emilio Marioni, Ian J. Deary, Qihua Tan

The paper identifies age-related DNA methylation patterns on the X-chromosome in males and females and finds sex differences in their association with mortality.

bioRxiv · May 14, 2019 · PreprintGenetics

Polygenic predictors of age-related decline in cognitive ability

Stuart James Ritchie, William David Hill, Riccardo Emilio Marioni, Gail Davies, Saskia P. Hagenaars, Sarah E. Harris, Simon R. Cox, Adele M. Taylor, Janie Corley, Alison Pattie, Paul H. Redmond, John M. Starr, Ian J. Deary

This study uses polygenic scores to predict cognitive ability at age 70 and cognitive change from 70 to 79, finding limited predictive validity compared to APOE e4.

Molecular Psychiatry · Feb 13, 2019Peer-reviewedGenomics

Brain Structural Differences Between 73- And 92-Year Olds Matched For Childhood Intelligence, Social Background, And Intracranial Volume

Stuart James Ritchie, David Alexander Dickie, Simon R. Cox, María del C. Valdés Hernández, Ruth Sibbett, Alison Pattie, Devasuda Anblagan, Paul H. Redmond, Natalie A. Royle, Janie Corley, Susana Muñoz Maniega, Adele M. Taylor, Sherif Karama, Tom Booth, Alan J. Gow, , Ian J. Deary

The paper matches 73- and 92-year-olds for childhood intelligence, social background, and brain size, finding significant structural brain differences linked to cognitive decline.

Neurobiology of Aging · Oct 16, 2017Peer-reviewedNeuroscience

An epigenome-wide association study of educational attainment (n = 10,767)

Richard Karlsson Linnér, Riccardo Emilio Marioni, Cornelius A. Rietveld, Andrew J. Simpkin, Neil M Davies, Kyoko Watanabe, Nicola J. Armstrong, Kirsi M. Auro, Clemens Baumbach, Marc Jan Bonder, Jadwiga Buchwald, Giovanni Fiorito, Khadeeja Ismail, Stella Iurato, Anni Joensuu, , Daniel Jacob Benjamin

This study investigates the association between CpG methylation and educational attainment, finding limited significant associations that may be influenced by confounding factors.

bioRxiv · Mar 7, 2017 · PreprintGenetics