Author

Youxian Li

Oslo University HospitalORCID 0000-0003-3213-1358Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Elise SolliiD· 1 shared Ingvild B. Johnsen· 1 shared Kjetil TaskéniD· 1 shared Nathaniel Edward Bennett SaiduiD· 1 shared Qian WeiiD· 1 shared Shixiong WangiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 10 mutual co-author links

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1 shared paperImmunology

Elise SolliORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJul 15, 2026

The Fas-FADD-caspase-8 axis is a cancer cell-intrinsic determinant of cytotoxic lymphocyte-mediated killing

Elise Solli, Shixiong Wang, Qian Wei…·Youxian Li

This study identifies the Fas-FADD-caspase-8 axis as a critical determinant of cancer cell susceptibility to cytotoxic lymphocyte killing, independent of executioner caspases.

DOI 10.64898/2026.06.14.732110

humangenetic perturbation / CRISPR

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ImmunologybioRxivPreprintMay 28, 2018

Osmolality controls the expression of cathelicidin antimicrobial peptide in human macrophages

Youxian Li, Ingvild B. Johnsen

This study shows that osmolality regulates cathelicidin antimicrobial peptide expression in human macrophages via NFAT5 and p38 MAPK, with TLR activation inhibiting this response.

DOI 10.1101/332635

humanexperimental assay

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