Author

George C. Gabriel

University of PittsburghORCID 0000-0003-3250-2518Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Cecilia W. Y. LoiD· 3 shared Abha Singh BaisiD· 2 shared Hisato YagiiD· 2 shared Yijen Lin WuiD· 2 shared Ashok PanigrahyiD· 1 shared Benjamin J. GlennoniD· 1 shared Bhaven B. PateliD· 1 shared Bruce J. AronowiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersDevelopmental Biology

Cecilia W. Y. LoORCID

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3 papers

Recent·Most cited

Developmental BiologyNature CommunicationsPeer-reviewedJan 7, 2025

Mitotic Block and Epigenetic Repression Underlie Neurodevelopmental Defects and Neurobehavioral Deficits in Congenital Heart Disease

George C. Gabriel, Hisato Yagi, Tuantuan Tan…·Cecilia W. Y. Lo

This study identifies mitotic block and epigenetic repression as causes of neurodevelopmental defects and neurobehavioral deficits in congenital heart disease using mouse models.

5 citations

mousebulk RNA-seq

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Developmental BiologybioRxivPreprintApr 21, 2023

Spatial transcriptome profiling uncovers metabolic regulation of left-right patterning

Hisato Yagi, Cheng Cui, Manush Saydmohammed…·Cecilia W. Lo

The paper identifies metabolic regulation in left-right patterning using spatial transcriptome data, linking glycolysis and Bmp7 to heart and gut looping.

1 citation

mousezebrafish

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Developmental BiologyDevelopmentPeer-reviewedSep 6, 2021

Gene-teratogen interactions influence the penetrance of birth defects by altering Hedgehog signaling strength

Jennifer H. Kong, Cullen B. Young, Ganesh Varma Pusapati…·Rajat Rohatgi

The paper shows that gene-teratogen interactions affect birth defect penetrance by altering Hedgehog signaling through the MMM complex and SMO degradation.

15 citations

mouseexperimental assay

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