Mitotic Block and Epigenetic Repression Underlie Neurodevelopmental Defects and Neurobehavioral Deficits in Congenital Heart Disease
George C. Gabriel, Hisato Yagi, Tuantuan Tan, Abha Singh Bais, Benjamin J. Glennon, Margaret Caroline Stapleton, Lihua Huang, William T. Reynolds, Marla G. Shaffer, Madhavi K. Ganapathiraju, Dennis W. Simon, Ashok Panigrahy, Yijen Lin Wu, Cecilia W. Y. Lo
This study identifies mitotic block and epigenetic repression as causes of neurodevelopmental defects and neurobehavioral deficits in congenital heart disease using mouse models.
Nature Communications · Jan 7, 2025Peer-reviewedDevelopmental Biology