Amyloid precursor protein induces reactive astrogliosis
Gretsen Velezmoro Jáuregui, Dragana Vukić, Isaac G. Onyango…·Gorazd Bernard Stokin
This study shows APP induces reactive astrogliosis in vitro and in vivo by remodeling intermediate filaments, enhancing cytokine production, and activating the IFN pathway.