Mária E. Čarná

Multiple motor proteins regulate ALS-linked TDP-43 anterograde axonal transport

The paper investigates TDP-43's anterograde axonal transport in human neurons, revealing its interaction with multiple kinesin motors and implications for ALS pathology.

Rethinking Alzheimers: Novel miRNAs Illuminate a Disease Beyond the Brain

This study identifies 194 miRNAs with widespread changes in Alzheimer's disease, including novel miRNAs not previously linked to AD, revealing new biological pathways and suggesting AD may be a systemic disorder.

Amyloid precursor protein induces reactive astrogliosis

This study shows APP induces reactive astrogliosis in vitro and in vivo by remodeling intermediate filaments, enhancing cytokine production, and activating the IFN pathway.

Unraveling axonal mechanisms of traumatic brain injury

This study investigates axonal swellings (AS) formation after traumatic brain injury, showing that AS occur independently of Ca2+ changes and involve cytoskeletal rearrangements that preserve axonal function.