Author

Sin Wah Tooki Chu

University College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Helena Tolarová· 2 shared Pavel TolariD· 2 shared Benjamin SaleiD· 1 shared Clare ThomasiD· 1 shared Dinis Pedro CaladoiD· 1 shared Faruk RamadaniiD· 1 shared Francesco ForconiiD· 1 shared Jessica OkosuniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Helena Tolarová

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 1, 2026

Altered PI3K-PTEN balance promotes preferential killing of human IgE+ plasma cells by BCR crosslinking

Faruk Ramadani, Helena Tolarová, Sin Wah Tooki Chu…·Pavel Tolar

The paper shows that human IgE+ plasma cells are selectively killed by BCR crosslinking due to a JNK/PTEN/BIM signaling axis, distinct from mouse mechanisms, and highlights therapeutic implications for anti-IgE antibodies.

DOI 10.64898/2026.05.28.728415

humanproteomics

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ImmunologybioRxivPreprintApr 12, 2024

Mutations in the IgG B cell receptor associated with class-switched B cell lymphomas

Laabiah Wasim, Sin Wah Tooki Chu, Benjamin Sale…·Pavel Tolar

This study identifies mutations in the IgG heavy chain in follicular lymphoma and EZB DLBCL that enhance BCR signalling and oncogenicity by disrupting the IgG intracellular tail.

3 citations

humanproteomics

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