Author

Alex Yu

Icahn School of Medicine at Mount Sinai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Aiqun LiiD· 3 shared Kristen BrennandiD· 3 shared Bin ZhangiD· 2 shared Minghui WangiD· 2 shared Nadine SchrodeiD· 2 shared Bin ZhangiD· 1 shared Calwing LiaoiD· 1 shared Carina SeahiD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersNeuroscience

Aiqun LiORCID

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Author profile →

3 papers

Recent·Most cited

Convergent coexpression of autism associated genes suggests some novel risk genes may not be detectable in large-scale genetic studies

Calwing Liao, Mariana Moysés‐Oliveira, Celine E. de Esch, Riya Bhavsar, Xander Nuttle, Aiqun Li, Alex Yu, Nicholas D. Burt, Serkan Erdin, Jack M. Fu, Minghui Wang, Theodore J. Morley, Lide Han, Patrick A. Dion, Guy Armand Rouleau, , Douglas M. Ruderfer

The paper identifies novel autism risk genes by analyzing convergent coexpression patterns in brain samples, showing these genes may not be detected by sequencing studies.

Cell Genomics · Mar 9, 2023Peer-reviewedGenetic & Genomic Medicine

Convergent and non-additive impact of schizophrenia risk genes in human neurons

PJ Michael Deans, Kayla G. Townsley, Aiqun Li, Carina Seah, Jessica Johnson, Judit García‐González, Evan Cao, Nadine Schrode, Alex Yu, Sam Cartwright, Georgios Voloudakis, Wen Zhang, Minghui Wang, John F. Fullard, Kiran Girdhar, , Kristen Brennand

This study shows that schizophrenia risk genes have convergent and non-additive transcriptomic effects when perturbed together in human neurons, suggesting functional redundancy and complex interactions.

bioRxiv · Mar 29, 2022 · PreprintNeuroscience

Molecular Networks and Key Regulators of the Dysregulated Neuronal System in Alzheimer’s Disease

Minghui Wang, Aiqun Li, Michiko Sekiya, Noam D. Beckmann, Xiuming Quan, Nadine Schrode, Michael B. Fernando, Alex Yu, Li Zhu, Jiqing Cao, Liwei Lyu, Emrin Horgusluoglu, Qian Wang, Lei Ming Guo, Yuanshuo Wang, , Bin Zhang

This study identifies molecular networks and key regulators in Alzheimer’s Disease using integrative genomics and experimental validation.

bioRxiv · Oct 1, 2019 · PreprintNeuroscience