Author

Christy Susan Varghese

University of BirminghamORCID 0000-0003-3312-0159Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Adam T. GrundhoffiD· 1 shared Aditi KanhereiD· 1 shared Akhil BowryiD· 1 shared Alexandra K. Walker· 1 shared Andrew David BeggsiD· 1 shared Boris NoyvertiD· 1 shared C. David Wood· 1 shared Claire WilsoniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMicrobiology

Adam T. GrundhoffORCID

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2 papers

Recent·Most cited

Molecular BiologyNucleic Acids ResearchPeer-reviewedOct 24, 2026

The 7SK small nuclear ribonucleoprotein links the cell responses to transcription and replication stress by promoting replication fork reversal and homologous recombination

Akhil Bowry, Claire Wilson, Richard D. Kelly…·Eva Petermann

This study shows that 7SK-snRNP components HEXIM1 and LARP7 promote replication fork reversal and homologous recombination under transcription and replication stress, independent of BRCA1.

DOI 10.1093/nar/gkag1021

humanexperimental assay

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MicrobiologyPLoS PathogensPeer-reviewedJan 27, 2025

Repression of CADM1 transcription by HPV type 18 is mediated by three-dimensional rearrangement of promoter-enhancer interactions

Karen Campos-León, Jack Ferguson, Thomas Günther…·Joanna L. Parish

This study shows that HPV18 infection reprograms host transcription by altering CTCF binding and promoter-enhancer interactions, leading to repression of the tumor suppressor CADM1.

3 citations

humanbulk RNA-seq

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