Author

Akhil Bowry

University of BirminghamORCID 0009-0004-0850-039XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Eva PetermanniD· 3 shared Alexandra K. Walker· 2 shared Ann Liza Piberger· 2 shared Joanna R. MorrisiD· 2 shared Richard D. KellyiD· 2 shared Aditi KanhereiD· 1 shared Aidan J. DohertyiD· 1 shared Christy Susan VargheseiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersMolecular Biology

Eva PetermannORCID

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3 papers

Recent·Most cited

Molecular BiologyNucleic Acids ResearchPeer-reviewedOct 24, 2026

The 7SK small nuclear ribonucleoprotein links the cell responses to transcription and replication stress by promoting replication fork reversal and homologous recombination

Akhil Bowry, Claire Wilson, Richard D. Kelly…·Eva Petermann

This study shows that 7SK-snRNP components HEXIM1 and LARP7 promote replication fork reversal and homologous recombination under transcription and replication stress, independent of BRCA1.

DOI 10.1093/nar/gkag1021

humanexperimental assay

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Molecular BiologyNature CommunicationsPeer-reviewedNov 17, 2020

PrimPol-dependent single-stranded gap formation mediates homologous recombination at bulky DNA adducts

Ann Liza Piberger, Akhil Bowry, Richard D. Kelly…·Eva Petermann

This study shows that PrimPol creates single-stranded gaps at bulky DNA adducts, which recruit RAD51 for homologous recombination, facilitating DNA repair in mammalian cells.

118 citationstop 3%

humanDNA methylation

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Molecular BiologyCell ReportsPeer-reviewedNov 1, 2018

BET inhibition induces HEXIM1- and RAD51-dependent conflicts between transcription and replication

Akhil Bowry, Ann Liza Piberger, Patricia Rojas…·Eva Petermann

This study shows BET inhibition causes replication stress through transcription-replication interference, involving HEXIM1 and RAD51, and reveals a new mechanism for BRD4's role in DNA replication and recombination.

52 citations

humanmouse

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