Lauren A. Lau

This study evaluates synthetic kainic acid injection parameters in the IHK model to reliably induce seizures while minimizing mortality.

This study shows that mild perinatal hypoxia-ischemia causes delayed and prolonged neuronal death, with neurons dying later showing normal function and viability for days post-injury.

The paper measures extracellular chloride concentrations in the brain and finds they are lower and more variable than previously thought due to displacement by immobile anions, affecting GABAA receptor function.

This study identifies the cellular sources of ictal population signals in seizures using calcium imaging and electrophysiology in mouse models.