Kuan Pang

Perturb-ME combines CRISPR screening and single-cell profiling to identify regulatory modules governing gene programs in melanoma.

PULSAR is a foundation model that integrates multi-scale biological data to predict disease and clinical outcomes in the human immune system.

LUMI-lab autonomously designs ionizable lipids for mRNA delivery, identifying brominated tails and achieving 20.3% gene editing efficacy in mice.

This paper introduces 3UTRBERT, a Transformer-based model for analyzing 3UTR sequences, achieving better performance in predicting RBP binding, m6A sites, and RNA localization.

A generative transformer pretrained on over 33 million cells can be fine-tuned for cell-type annotation, batch and multi-omic integration, perturbation prediction and gene network inference, claiming superior performance.