Thomas H. Mosley

This paper identifies a novel genetic locus associated with olfactory dysfunction through a genome-wide association study meta-analysis and shows causal links to various health outcomes.

This study uses whole-genome sequence data from diverse participants to identify novel genetic loci associated with brain structural volumes, highlighting the importance of diverse cohorts in uncovering genetic architecture.

This paper conducts multi-ancestry transcriptome-wide association studies to identify genes associated with cognitive function, white matter hyperintensity, and Alzheimer's disease using gene expression data from European and African ancestry individuals.

This study identifies genetic loci specific to periventricular and deep white matter hyperintensities, revealing distinct genetic architectures and potential biological mechanisms.

The paper identifies 161 genome-wide significant genetic associations for cortical structure traits across 34 brain regions, highlighting key biological pathways and gene functions.

The paper identifies genetic associations with cortical surface area using PCA and GWAS, linking DAAM1 to visual cortex development through mitochondrial pathways and thalamocortical input.

The paper identifies 25 genetic loci associated with subcortical brain structure volumes in over 40,000 individuals, revealing novel biology and potential drug targets.