PhysiologyArteriosclerosis Thrombosis and Vascular BiologyPeer-reviewed
Vascular endothelial growth factor receptors 1 and 3 mediate placental trophoblast leptin production in preeclampsia, inducing vascular dysfunction
Mona Elgazzaz, Safia N. Ogbi, Desmond Moronge…·Jessica Faulkner
This study shows that sFlt-1 in preeclampsia increases trophoblast leptin production via VEGFR1 and 3, leading to vascular dysfunction.