Tomas C. Pascoa

The anaerobic cryo-EM structure of the methanogenic Mtr complex reveals a nitrogenase-like cluster bound to its active site

The paper presents cryo-EM structures of the Mtr complex from Methanosarcina mazei, revealing a novel [Fe8S9C] cluster near the catalytic site and suggesting a link between methyl transfer and Na+ translocation.

Coupling of electron-bifurcation modules powers aromatic ring reduction beyond the biological redox window

This study reveals how BCRII enzymes use electron-bifurcation modules to reduce aromatic rings beyond typical biological redox limits.

Structure of the energy converting methyltransferase (Mtr) of Methanosarcina mazei in complex with an oxygen-stress responsive small protein

The paper presents a cryo-EM structure of the Mtr complex from Methanosarcina mazei and identifies a small ORF protein, MtrI, involved in oxygen stress response.