Ranjit Manchanda

This study reconstructs transcriptional trajectories of Fallopian-tube epithelium to show STICs occupy diverse positions along a progression continuum and exhibit variable PARPi resistance signatures.

This paper evaluates a streamlined germline genetic testing pathway for breast cancer patients, showing high satisfaction and feasibility while highlighting the need for simplified criteria to improve detection of pathogenic variants.

The paper shows that modifying the tumor microenvironment's extracellular matrix improves chemotherapy response in ovarian cancer models.

This study compares digital and in-person genetic counseling for germline testing in breast cancer patients, finding higher uptake with digital information without compromising other outcomes.

The paper develops a multifactorial risk model for epithelial tubo-ovarian cancer incorporating genetic and epidemiological factors to stratify risk and guide screening.