Author

Rikesh M. Rajani

InsermORCID 0000-0003-3391-8654Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Anne JouteliD· 1 shared Carlo Sala FrigerioiD· 1 shared Charles ArberiD· 1 shared Cyril PouponiD· 1 shared David André BarrièreiD· 1 shared David KlenermaniD· 1 shared David R. GraykowskiiD· 1 shared Emre FertaniD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Anne JoutelORCID

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2 papers

Recent·Most cited

NeurosciencePLoS BiologyPeer-reviewedJul 23, 2024

Selective suppression of oligodendrocyte-derived amyloid beta rescues neuronal dysfunction in Alzheimer's Disease

Rikesh M. Rajani, Robert A. Ellingford, Mariam Hellmuth…·Marc Aurel Busche

This study shows that oligodendrocytes produce amyloid beta in Alzheimer's Disease and that suppressing this production improves brain pathology and neuronal function.

60 citationstop 1%

mouseexperimental assay

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NeurosciencebioRxivPreprintFeb 27, 2023

Characterization of early white matter changes in CADASIL using microscopic diffusion imaging and relaxometry

David André Barrière, Ivy Uszynski, Rikesh M. Rajani…·Anne Joutel

This study uses diffusion MRI and relaxometry to identify microstructural changes in white matter of CADASIL mice, finding increased extracellular free water and reduced myelin content.

DOI 10.1101/2023.02.27.530286

mousebulk RNA-seq

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