Marc Aurel Busche

Interpreting Sleep Activity Through Neural Contrastive Learning

The paper develops a neural network model, Sleep Interpreter (SI), to decode memory replay from sleep EEG and shows it can accurately detect reactivation during sleep that correlates with memory performance.

Selective suppression of oligodendrocyte-derived amyloid beta rescues neuronal dysfunction in Alzheimer's Disease

This study shows that oligodendrocytes produce amyloid beta in Alzheimer's Disease and that suppressing this production improves brain pathology and neuronal function.

PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons

The paper generates C9orf72 DPR knock-in mice and identifies an extracellular matrix signature in C9ALS/FTD that is conserved across species and protected by TGF-β1 and COL6A1.