Katarzyna Unrug-Bielawska

This study shows that mature tumoroids, grown in 3D culture for ≥10 days, better reflect clinical drug responses in PDAC compared to short-term cultures by capturing microenvironmental effects and transporter-mediated resistance.

This study shows that 3D cultures of pancreatic cancer cells better replicate the mitochondrial oxidative phosphorylation genotype seen in vivo compared to 2D cultures.